API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/EP
C22H24ClN5O2
6-chloro-3- [1 [3 (2 oxo 3H benzimidazol 1 yl) propyl] piperidin 4 yl] 1H benzimidazol 2 one
57808-66-9
425.91 g/mol
Benzimidazole derivatives
Anti-Emetic
| Appearance | Off-White Crystalline Solid |
|---|---|
| Solubility | Freely soluble in chloroform |
| Melting point | 242.5 °C |
| pH | 4.0 – 5.5 |
Domperidone is an antiemetic (anti-sickness) and prokinetic drug. It belongs to a group of drugs called dopamine antagonists. It is used to treat stomach-related issues, such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased movement of the stomach and upper gastrointestinal (GI) tract. It is also used to boost breastmilk supply.
Domperidone works by blocking dopamine receptors in the gut. It increases the movement or contractions of the muscles in your stomach and intestines, increasing how quickly and easily food moves through your digestive tract. It also acts on the chemoreceptor trigger zone in your brain, which is involved in nausea and vomiting. This area of your brain is outside the blood-brain barrier. Unlike other dopamine antagonists, domperidone does not cross the blood-brain barrier, which minimizes central nervous system (CNS) side effects.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Domperidone is used to relieve nausea, vomiting, bloating, and improve gastric motility in conditions like gastroparesis and reflux.
It blocks dopamine D₂ receptors in the gut and brain (specifically the chemoreceptor trigger zone), helping reduce nausea and improve stomach emptying.
Generally yes, when used as prescribed. However, high doses or long-term use may increase the risk of heart rhythm problems, especially in elderly patients.
Yes, but avoid combining it with drugs that prolong the QT interval (heart rhythm) unless advised by a doctor.
Yes, Salius Pharma exports Domperidone API to several African countries including Nigeria, Kenya, South Africa, and Ghana. As a globally recognized ISO-certified Star Export House, they supply high-quality APIs across the continent. For specific details about orders, registration, and delivery, it is best to contact Salius Pharma directly through their official website.
Looking to source Domperidone or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.