API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/USP
C27H30F6N2O2
(5α,17β)-N-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide
164656-23-9
528.53 g/mol
Steroid derivatives
Anti-BPH
| Appearance | Off-White Crystalline Solid |
|---|---|
| Solubility | Highly soluble in DMSO |
| Melting point | 242–250 °C |
| pH | Less than 2 |
Dutasteride is a synthetic 4-azasteroid compound that selectively inhibits both the type I and type II isoforms of steroid 5α-reductase, an intracellular enzyme that converts testosterone to 5α-dihydrotestosterone (DHT). Dutasteride works by reducing the levels of circulating DHT. It was also shown to reduce the size of the prostate gland, improve urinary flow, and symptoms of benign prostatic hyperplasia alone or in combination with tamsulosin.
Dutasteride works by inhibiting both type I and type II isoforms of the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT), a hormone that plays a key role in prostate growth and hair loss. By significantly reducing DHT levels in the blood and tissues (by over 90%), dutasteride helps shrink an enlarged prostate in men with benign prostatic hyperplasia (BPH), improving urinary flow and symptoms. It may also slow or prevent hair loss by reducing DHT activity in hair follicles, although this use is considered off-label in some regions.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Dutasteride API is the pure, active pharmaceutical ingredient used to formulate medications for treating benign prostatic hyperplasia (BPH) and, off-label, male pattern baldness.
Dutasteride inhibits type I and type II 5-alpha reductase enzymes, reducing the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to prostate growth and hair loss.
No, it is not recommended for women, especially those who are or may become pregnant, due to the risk of fetal harm.
Serum testosterone levels may increase slightly (10–20%) due to feedback inhibition after DHT reduction, but it usually remains within the normal range.
Yes, Salius Pharma exports Dutasteride API to several African countries, including Nigeria, Kenya, South Africa, Egypt, Ghana, Tanzania, Uganda, Ethiopia, Morocco, and Algeria. Their broad export network and certifications (WHO-GMP, USFDA, UK MHRA) support their presence across these regions in Africa.
Looking to source Dutasteride or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.