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Nebivolol Structure

Product Type

API

Grade

IP

Chemical Formula

C22H25F2NO4

IUPAC Name

1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino}ethan-1-ol

CAS NO

99200-09-6

Molecular Weight

405.44 g/mol

Chemical Class

beta-1 selective beta-adrenergic receptor blockers

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to off-white crystalline powder
Solubility Slightly soluble in water; soluble in organic solvents like ethanol and methanol
Melting point 220°C to 228°C
pH 1.0 to 5.0

Product Description

Nebivolol is a medication classified as a beta-blocker, primarily used to treat high blood pressure (hypertension) and sometimes heart failure. It works by blocking beta-1 adrenergic receptors in the heart, which slows the heart rate and reduces the force of contraction, helping to lower blood pressure and decrease the heart's workload.

How Nebivolol Works

Selective beta-1 blocker with additional nitric oxide–mediated vasodilation effects, which can help relax blood vessels.

Use(s)

Adverse Effects

Why choose Salius for Nebivolol?

  1. Regulatory-Grade Manufacturing Standards
    They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release.
  2. Cost-Effectiveness
    As a generic manufacturer and export house, Salius aims to deliver high-quality APIs at competitive prices—a key advantage for cost-sensitive markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

Unlike traditional beta-blockers that mainly reduce heart rate and contractility, nebivolol also stimulates endothelial nitric oxide production, causing blood vessels to relax and widen. This dual action can improve blood flow and may cause fewer side effects like cold extremities.

Yes, studies suggest nebivolol is effective and well-tolerated in elderly patients, partly due to its vasodilatory properties which may improve arterial compliance, making it a preferred beta-blocker in this group.

Yes, some research indicates nebivolol has antioxidant effects, which may contribute to cardiovascular protection by reducing oxidative stress in blood vessels.

Salius Pharma supplies Nebivolol as an Active Pharmaceutical Ingredient (API).

To order Nebivolol API, you typically contact a certified pharmaceutical supplier like Salius Pharma. You'll need to provide details such as desired quantity, intended market, regulatory requirements (e.g., DMF or GMP certificates), and packaging preferences.

Salius Pharma exports Nebivolol to various countries worldwide, including regions such as Asia, Europe, the Middle East, Africa, North America & South America.

Place an Order or Request a Quote

Looking to source Nebivolol or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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