API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/USP/EP
C₂₈H₂₈O₃
6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid
106685-40-9
412.52 g/mol
Retinoid Analogue
Anti-acne / Keratolytic Agent
| Appearance | White to faintly yellow crystalline powder |
|---|---|
| Solubility | Slightly soluble in alcohol; Insoluble in chloroform and ether; Soluble in dilute alkali solutions |
| Melting point | 255–265 °C (with decomposition) |
| pH | 4.5–6.0 |
Adapalene is a third-generation synthetic retinoid used primarily for acne treatment. It works by regulating keratinocyte differentiation, reducing microcomedone formation, and providing anti-inflammatory effects. Due to its stable chemical structure, Adapalene is less irritating than older retinoids and offers better photostability, making it suitable for long-term dermatological formulations such as gels, creams, and lotions.
Adapalene inhibits the enzyme carbonic anhydrase, reducing the formation of hydrogen and bicarbonate ions.
This leads to:
Reduced aqueous humor formation → ↓ intraocular pressure
Increased bicarbonate excretion → diuresis
Mild metabolic acidosis → ↑ ventilation
Neuronal stabilization → antiepileptic effect
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO-GMP, ISO 9001:2015, FDA-audited facilities |
| Affordability & Generic Access | Cost-competitive generics for global supply |
| Export Experience | Proven record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Salius Pharma offers Adapalene that complies with BP, USP, and EP pharmacopeial standards, ensuring global acceptability. Each batch undergoes stringent quality checks, impurity profiling, and stability monitoring to ensure consistent, reproducible quality.
We maintain controlled production cycles, validated processes, and GMP-compliant facilities. With strong export capabilities and ready documentation, Salius ensures consistent supply, minimal lead times, and uninterrupted availability for international clients.
Standard packaging includes 25 kg HDPE drums with double-liner protection to maintain product integrity. Customized packaging is available for R&D, pilot batches, or regulatory submissions.
Yes. We provide COA, MSDS, stability data, MOA, TDS, and process-related documents as needed. Our technical team supports clients throughout regulatory submissions and product development stages.
Yes, we offer sample quantities for formulation development, stability studies, and pilot manufacturing. Clients can request samples through our technical or commercial team.
We maintain controlled production cycles, validated processes, and GMP-compliant facilities. With strong export capabilities and ready documentation, Salius ensures consistent supply, minimal lead times, and uninterrupted availability for international clients.
Looking to source Adapalene or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.