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Cefpodoxime Proxetil Structure

Product Type

API

Grade

BP/USP

Chemical Formula

C21H27N5O9S2

IUPAC Name

(1RS)-1-[[(1-Methylethoxy)carbonyl]oxy]ethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

CAS No.

87239-81-4

Molecular Weight

557.60 g/mol

Chemical Class

Cephalosporins

Therapeutic Class

Antibiotic- Cephalosporins

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to slightly yellowish powder
Solubility Practically insoluble in water, slightly soluble in methanol and ethanol, soluble in dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF)
Melting point 108–113 °C
pH 4.0 to 5.5

Product Description

Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram-negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.

How Cefpodoxime Proxetil Works

Cefpodoxime is active against a wide spectrum of Gram-positive and Gram-negative bacteria. Cefpodoxime is stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and cephalosporins, due to their production of beta-lactamase, may be susceptible to cefpodoxime. Cefpodoxime is inactivated by certain extended spectrum beta-lactamases. The bactericidal activity of cefpodoxime results from its inhibition of cell wall synthesis. The active metabolite of cefpodoxime binds preferentially to penicillin binding protein 3, which inhibits production of peptidoglycan, the primary constituent of bacterial cell walls.

Use(s)

Adverse Effects

Why choose Salius for Cefpodoxime Proxetil?

  1. Trusted Manufacturing with Global Quality Standards
    Salius complies with WHO-GMP across all facilities, with select sites also approved by the U.S. FDA. Every batch undergoes rigorous laboratory testing to guarantee safety, quality, and full regulatory compliance.
  2. Large-Scale API Production with Competitive Pricing
    Leveraging extensive manufacturing capacity and efficient global distribution, Salius delivers high-quality APIs at competitive prices, supporting pharmaceutical companies in cost-sensitive markets worldwide.
  3. Global Export Expertise and Comprehensive Documentation Support
    Salius has experience exporting APIs worldwide, offering full regulatory documentation including Drug Master Files (DMF) and impurity profiles. We provide dedicated support for regulatory filings to help international clients, even in highly regulated markets, ensure smooth approval and compliance.
  4. Documents We Provide
  5. Proven Reliability
    Salius Pharma is presented as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO-GMP, ISO 9001:2015, FDA-audited facilities
Affordability & Generic Access Cost-competitive generics for global supply
Export Experience Proven record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

Place an Order or Request a Quote

Looking to source Cefpodoxime Proxetil or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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