Dapoxetine

Synonyms

• Dapoxetina, Dapoxetine, Dapoxetinum

PHYSIOCHEMICAL PROPERTIES

Product Description

Dapoxetine, sold under the brand name Priligy among others, is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation (PE) in men ages 18 to 64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay. As a member of the SSRI family, dapoxetine was initially created as an antidepressant.

How Dapoxetine Works

The drug's mechanism of action is thought to be related to inhibition of neuronal reuptake of serotonin and subsequent potentiation of serotonin activity. The central ejaculatory neural circuit comprises spinal and cerebral areas that form a highly interconnected network. The sympathetic, parasympathetic, and somatic spinal centers, under the influence of sensory genital and cerebral stimuli integrated and processed at the spinal cord level, act in synergy to command physiologic events occurring during ejaculation. Experimental evidence indicates that serotonin (5-HT), throughout brain descending pathways, exerts an inhibitory role on ejaculation. To date, three 5-HT receptor subtypes (5-HT(1A), 5-HT(1B), and 5-HT(2C)) have been postulated to mediate 5-HT's modulating activity on ejaculation.

Use(s)

• Primarily prescribed for premature ejaculation (PE) in men.
• It works by inhibiting serotonin reuptake, which increases serotonin levels and helps delay ejaculation.

Adverse Effects

• Nausea
• Headache
• Dizziness
• Dry mouth
• Diarrhea
• Insomnia

Why choose Salius for Dapoxetine?

1. 1. Trusted Manufacturing with Global Quality Standards
   Salius complies with WHO-GMP across all facilities, with select sites also approved by the U.S. FDA. Every batch undergoes rigorous laboratory testing to guarantee safety, quality, and full regulatory compliance.
2. 2. Large-Scale API Production with Competitive Pricing
   Leveraging extensive manufacturing capacity and efficient global distribution, Salius delivers high-quality APIs at competitive prices, supporting pharmaceutical companies in cost-sensitive markets worldwide.
3. Global Export Expertise and Comprehensive Documentation Support
   Salius has experience exporting APIs worldwide, offering full regulatory documentation including Drug Master Files (DMF) and impurity profiles. We provide dedicated support for regulatory filings to help international clients, even in highly regulated markets, ensure smooth approval and compliance.

4. Proven Reliability
   Salius Pharma is presented as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Dapoxetine
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.