API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP/USP
C17H22ClNO
2-(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride
147-24-0
291.82 g/mol
Ethanolamine
Antihistamine
| Appearance | Off-White Crystalline Solid |
|---|---|
| Solubility | Very soluble in water and freely soluble in alcohol |
| Melting point | 168-172 °C |
| pH | 4.0 – 5.5 |
Diphenhydramine HCl is an antihistamine used to relieve symptoms of allergies, hay fever, and the common cold, such as sneezing, runny nose, itchy eyes, and throat irritation. It is also used to treat itching and skin irritations from insect bites or sunburn, prevent and treat motion sickness, and manage short-term insomnia due to its sedative effects. Additionally, it can help control symptoms of Parkinson’s disease and is sometimes included in cough and cold products as a suppressant.
Diphenhydramine HCl works by blocking the effects of histamine, a chemical released by the body during allergic reactions. It is a first-generation antihistamine that crosses the blood-brain barrier and binds to H1 histamine receptors, preventing histamine from attaching and triggering allergy symptoms like itching, swelling, and runny nose. Additionally, its ability to block muscarinic receptors in the brain leads to sedative and anti-nausea effects, which is why it also helps with motion sickness, insomnia, and certain Parkinson’s symptoms.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Countries with higher prevalence of amoebiasis such as Africa, Latin America, Southeast Asia, and the Middle East drive strong market demand.
It works by blocking histamine (H1) receptors, which reduces allergic symptoms like sneezing, itching, runny nose, and watery eyes. It also has sedative effects.
Yes, due to its sedating properties, it’s commonly used in over-the-counter sleep aids. However, it should not be used long-term for insomnia.
It may be used in pregnancy if clearly needed, but always consult a healthcare provider. It can pass into breast milk and may affect a nursing infant.
Yes, Salius Pharma Pvt. Ltd. exports Diphenhydramine Hydrochloride API. We are an ISO 9001:2015 certified Star Export House based in India, well-established as a global supplier of high-quality APIs for export markets, including antihistamines like Diphenhydramine HCl.
Looking to source Diphenhydramine HCl or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.