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Donepezil HCL Monohydrate Structure

Product Type

API

Grade

USP

Chemical Formula

C24H32ClNO4

IUPAC Name

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride monohydrate

CAS No.

884740-09-4

Molecular Weight

415.96 g/mol

Chemical Class

Piperidine derivatives

Therapeutic Class

Acetyl cholinesterase Inhibitors

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance Off-White Crystalline Solid
Solubility Freely soluble in chloroform
Melting point 220–225 °C
pH 2.0 to 3.0

Product Description

Donepezil HCL Monohydrate (brand name Aricept) may be used to treat dementia caused by Alzheimer's disease. Donepezil can help improve attention, memory, behavior, and ability to do daily activities in dementia patients. Donepezil is not a cure for Alzheimer's disease; it may help improve symptoms, but the condition will progress over time, even in people who take this medicine. Research has determined that donepezil is effective in mild, moderate, and severe Alzheimer's disease.

How Donepezil HCL Monohydrate Works

Donepezil hydrochloride monohydrate works by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine in the brain. By blocking this enzyme, donepezil increases the levels of acetylcholine, a chemical crucial for memory and cognitive function, thereby helping to improve communication between nerve cells and reduce symptoms of memory loss and cognitive decline, especially in patients with Alzheimer's disease.

Use(s)

Adverse Effects

Why choose Salius for Donepezil HCL Monohydrate?

  1. WHO-GMP Certified Manufacturing
    Salius Pharma produces Donepezil HCL Monohydrate in facilities certified by WHO-GMP, ensuring the API meets high-quality, safety, and purity standards required globally.
  2. Consistent Quality and Reliability
    Strict quality control protocols provide consistent, pharmaceutical-grade Donepezil HCL Monohydrate, helping avoid batch failures and regulatory issues.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs and provides DMFs, impurity profiles and other technical dossiers to support international clients.
  4. Documents We Provide
  5. Focus on Chronic Therapy APIs
    Salius specializes in APIs for chronic diseases, demonstrating expertise in producing reliable compounds like Donepezil HCL Monohydrate.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

Donepezil HCL Monohydrate is used to treat symptoms of mild to moderate Alzheimer's disease, such as memory loss, confusion, and problems with thinking and reasoning. It helps improve cognitive function by increasing levels of acetylcholine.

Donepezil works by inhibiting acetylcholinesterase, preventing breakdown of acetylcholine and thus improving nerve-cell communication and memory.

Yes, it is available for global export with complete documentation including COA, MOA, MSDS, TSE/BSE declaration, and regulatory filings (DMF/CEP).

Yes, Salius Pharma exports Donepezil HCL Monohydrate to African countries and other regions as part of their global distribution strategy.

Place an Order or Request a Quote

Looking to source Donepezil HCL Monohydrate or other high-quality pharmaceutical products? We’re here to help. Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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